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Role of the proto-oncogene Pokemon in cellular transformation and ARF repression

Maeda, Takahiro, Hobbs, Robin M., Merghoub, Taha, Guernah, Ilhem, Zelent, Arthur, Cordon-Cardo, Carlos, Teruya-Feldstein, Julie, Pandolfi, Pier Paolo

Journal:

Nature

Année:

2005

Langue:

english

Fichier:

PDF, 606 KB

english, 2005

Down-regulation of retinoic acid receptor activity associated with decreased α and γ isoforms expression in F9 embryonal carcinoma cells differentiated by retinoic acid

David Lazega, Esther Schenker, Nathalie Busso, Arthur Zelent, Alex Chen, Samuel Waxman

Journal:

Journal of Cellular Physiology

Année:

1993

Langue:

english

Fichier:

PDF, 860 KB

english, 1993

Genetic linkage analysis of the murine developmental mutant velvet coat (Ve) and the distal chromosome 15 developmental genes Hox-3.1, Rar-g, Wnt-1, and Krt-2

Charles P. Hart, John G. Compton, Stephen H. Langley, Lisa Hunihan, Kenneth P. LeClair, Arthur Zelent, Thomas H. Roderick, Frank H. Ruddle

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Année:

1992

Langue:

english

Fichier:

PDF, 1.14 MB

english, 1992

In situ-RT-PCR and immunohistochemistry for the localisation of the mRNA of the alpha 3 chain of laminin and laminin-5 during human organogenesis

Nicolai Miosge, Jens-Gerrit Kluge, Arthur Studzinski, Christina Zelent, Christa Bode, Patricia Sprysch, Robert E. Burgeson, Rainer Herken

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Année:

2002

Langue:

english

Fichier:

PDF, 938 KB

english, 2002

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

Zelent, Arthur, Krust, Andrée, Petkovich, Martin, Kastner, Philippe, Chambon, Pierre

Journal:

Nature

Année:

1989

Fichier:

PDF, 501 KB

1989

10.1038/89031

Zelent, Arthur

Journal:

Nature Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 168 KB

english, 2001

Reduced renal prepro-epidermal growth factor mRNA and decreased EGF excretion in ARF

Safirstein, Robert, Zelent, Arthur Z, Price, Peter M

Journal:

Kidney International

Année:

1989

Langue:

english

Fichier:

PDF, 595 KB

english, 1989

Distinct interactions of PML-RARα and PLZF-RARα with co-repressors determine differential responses to RA in APL

He, Li-Zhen, Guidez, Fabien, Tribioli, Carla, Peruzzi, Daniela, Ruthardt, Martin, Zelent, Arthur, Pandolfi, Pier Paolo

Journal:

Nature Genetics

Année:

1998

Fichier:

PDF, 1.24 MB

1998

Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARα fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient

Koken, Marcel HM, Daniel, Marie-Thérèse, Gianni, Maurizio, Zelent, Arthur, Licht, Jonathan, Buzyn, Agnes, Minard, Patricia, Degos, Laurent, Varet, Bruno, de Thé, Hugues

Journal:

Oncogene

Année:

1999

Langue:

english

Fichier:

PDF, 679 KB

english, 1999

Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZF

Dhordain, Philippe, Albagli, Olivier, Honore, Nicole, Guidez, Fabien, Lantoine, Danièle, Schmid, Michel, De The, Hugues, Zelent, Arthur, Koken, Marcel HM

Journal:

Oncogene

Année:

2000

Langue:

english

Fichier:

PDF, 677 KB

english, 2000

Translocations of the RARα gene in acute promyelocytic leukemia

Zelent, Arthur, Guidez, Fabien, Melnick, Ari, Waxman, Samuel, Licht, Jonathan D

Journal:

Oncogene

Année:

2001

Langue:

english

Fichier:

PDF, 557 KB

english, 2001

Regulation of Hoxb2 by APL-associated PLZF protein

Ivins, Sarah, Pemberton, Kieran, Guidez, Fabien, Howell, Louise, Krumlauf, Robb, Zelent, Arthur

Journal:

Oncogene

Année:

2003

Langue:

english

Fichier:

PDF, 484 KB

english, 2003

Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia

Zelent, Arthur, Greaves, Mel, Enver, Tariq

Journal:

Oncogene

Année:

2004

Langue:

english

Fichier:

PDF, 262 KB

english, 2004

Silencing of androgen-regulated genes using a fusion of AR with the PLZF transcriptional repressor

Pike, Joanna, Holmes, David, Kamalati, Tahereh, Davies, Derek, Tolhurst, Robert, Mazhar, Danish, Fishpool, Sam, al-Jehani, Rajai, Waxman, Jonathan, Zelent, Arthur

Journal:

Oncogene

Année:

2004

Langue:

english

Fichier:

PDF, 348 KB

english, 2004

Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A

Yeyati, Patricia L, Shaknovich, Rita, Boterashvili, Sima, Li, Jia, Ball, Helen J, Waxman, Samuel, Nason-Burchenal, Kathryn, Dmitrovsky, Ethan, Zelent, Arthur, Licht, Jonathan D

Journal:

Oncogene

Année:

1999

Langue:

english

Fichier:

PDF, 369 KB

english, 1999

Recruitment of RXR by Homotetrameric RARα Fusion Proteins Is Essential for Transformation

Bernd B. Zeisig, Colin Kwok, Arthur Zelent, Pattabhiraman Shankaranarayanan, Hinrich Gronemeyer, Shuo Dong, Chi Wai Eric So

Journal:

Cancer Cell

Année:

2007

Langue:

english

Fichier:

PDF, 2.29 MB

english, 2007

Fingering Modulators of Retinoic Acid Signaling Identifies New Prognostic Marker for Neuroblastoma

Hinrich Gronemeyer, Arthur Zelent

Journal:

Cancer Cell

Année:

2009

Langue:

english

Fichier:

PDF, 314 KB

english, 2009

TRANSLOCATION OF THE RARα LOCUS TO THE PML OR PLZF GENE IN ACUTE PROMYELOCYTIC LEUKAEMIA

Arthur Zelent

Journal:

British Journal of Haematology

Année:

1994

Langue:

english

Fichier:

PDF, 1.16 MB

english, 1994

Retinoic acid-induced glandular metaplasia in mouse skin is linked to the dermal expression of retinoic acid receptor β mRNA

Jean P. Viallet, Esther Ruberte, Stanislas du Manoir, Andrée Krust, Arthur Zelent, Danielle Dhouailly

Journal:

Developmental Biology

Année:

1991

Langue:

english

Fichier:

PDF, 3.55 MB

english, 1991

Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cells

Clara Nervi, Thomas M. Vollberg, Margaret D. George, Arthur Zelent, Pierre Chambon, Anton M. Jetten

Journal:

Experimental Cell Research

Année:

1991

Langue:

english

Fichier:

PDF, 2.91 MB

english, 1991

LRF Is an Essential Downstream Target of GATA1 in Erythroid Development and Regulates BIM-Dependent Apoptosis

Takahiro Maeda, Keisuke Ito, Taha Merghoub, Laura Poliseno, Robin M. Hobbs, Guocan Wang, Lin Dong, Manami Maeda, Louis C. Dore, Arthur Zelent, Lucio Luzzatto, Julie Teruya-Feldstein, Mitchell J. Weiss

Journal:

Developmental Cell

Année:

2009

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2009

Two Critical Hits for Promyelocytic Leukemia

Li-Zhen He, Mantu Bhaumik, Carla Tribioli, Eduardo M Rego, Sarah Ivins, Arthur Zelent, Pier Paolo Pandolfi

Journal:

Molecular Cell

Année:

2000

Langue:

english

Fichier:

PDF, 964 KB

english, 2000

Marked for death

Petrie, Kevin, Zelent, Arthur

Journal:

Nature Cell Biology

Année:

2008

Langue:

english

Fichier:

PDF, 509 KB

english, 2008

Molecular pathogenesis of acute promyelocytic leukaemia and APL variants

Andres Sirulnik, Ari Melnick, Arthur Zelent, Jonathan D Licht

Journal:

Best Practice & Research Clinical Haematology

Année:

2003

Langue:

english

Fichier:

PDF, 228 KB

english, 2003

Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes

Mattei, Marie-Geneviève, Rivière, Michèle, Krust, Andrée, Ingvarsson, Sigurdur, Vennström, Björn, Islam, M.Quamrul, Levan, Göran, Kautner, Philippe, Zelent, Arthur, Chambon, Pierre, Szpirer, Josiane,

Journal:

Genomics

Année:

1991

Langue:

english

Fichier:

PDF, 5.87 MB

english, 1991

Amino-Terminal Protein-Protein Interaction Motif (POZ-Domain) is Responsible for Activities of the Promyelocytic Leukemia Zinc Finger-Retinoic Acid Receptor-α Fusion Protein

Shuo Dong, Jun Zhu, Alan Reid, Philip Strutt, Fabien Guidez, Hao-Jie Zhong, Zhen-Yi Wang, Jonathan Licht, Samuel Waxman, Christine Chomienne, Zhu Chen, Arthur Zelent and Sai-Juan Chen

Journal:

Proceedings of the National Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 1.33 MB

english, 1996

Synthesis and Evaluation of a Potent and Selective Cell-Permeable p300 Histone Acetyltransferase Inhibitor

Zheng, Yujun, Balasubramanyam, Karanam, Cebrat, Marek, Buck, Donald, Guidez, Fabien, Zelent, Arthur, Alani, Rhoda M., Cole, Philip A.

Journal:

Journal of the American Chemical Society

Année:

2005

Langue:

english

Fichier:

PDF, 79 KB

english, 2005

Translational Selection in the Expression of the Hepatitis B Virus Envelope Proteins

PRICE, PETER M., MOHAMAD, ADEL, ZELENT, ARTHUR, NEURATH, A. ROBERT, ACS, GEORGE

Journal:

DNA

Année:

1988

Langue:

english

Fichier:

PDF, 4.75 MB

english, 1988

Differentiation therapy of acute myeloid leukemia: past, present and future

Petrie, Kevin, Zelent, Arthur, Waxman, Samuel

Journal:

Current Opinion in Hematology

Année:

2009

Langue:

english

Fichier:

PDF, 186 KB

english, 2009

SPIE Proceedings [SPIE Optics, Electro-Optics, and Laser Applications in Science and Engineering - Los Angeles, CA (Sunday 20 January 1991)] Photochemistry and Photoelectrochemistry of Organic and Inorganic Molecular Thin Films - Artificial photosynthesis at octane/water interface in the presence of hydrated chlorophyll a oligomer thin film

Volkov, Alexander G., Gugeshashvili, M. I., Kandelaki, M. D., Markin, V. S., Zelent, Bogumil, Munger, G., Leblanc, Roger M., Lawrence, Marcus F., Frank, Arthur J., Ramasesha, S., Wamser, Carl C.

Année:

1991

Langue:

english

Fichier:

PDF, 402 KB

english, 1991

RAR-β4, a Retinoic Acid Receptor Isoform is Generated from RAR-β2 by Alternative Splicing and Usage of a CUG Initiator Codon

Sunil Nagpal, Arthur Zelent and Pierre Chambon

Journal:

Proceedings of the National Academy of Sciences

Année:

1992

Langue:

english

Fichier:

PDF, 1023 KB

english, 1992

Lim Protein Ajuba Functions as a Nuclear Receptor Corepressor and Negatively Regulates Retinoic Acid Signaling

Zhaoyuan Hou, Hongzhuang Peng, David E. White, Dmitri G. Negorev, Gerd G. Maul, Yunfeng Feng, Gregory D. Longmore, Samuel Waxman, Arthur Zelent, Frank J. Rauscher and George F. Vande

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2010

PLZF-RARα Fusion Proteins Generated from the Variant t(11;17)(q23;q 21) Translocation in Acute Promyelocytic Leukemia Inhibit Ligand-Dependent Transactivation of Wild-Type Retinoic Acid Receptors

Zhu Chen, Fabien Guidez, Philippe Rousselot, Annissa Agadir, Sai-Juan Chen, Zhen-Yi Wang, Laurent Degos, Arthur Zelent, Samuel Waxman and Christine Chomienne

Journal:

Proceedings of the National Academy of Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 976 KB

english, 1994

Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells

Eduardo F. Farias, Kevin Petrie, Boris Leibovitch, Janice Murtagh, Manuel Boix Chornet, Tino Schenk, Arthur Zelent, Samuel Waxman and Zhu Chen

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2010

Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases

McConnell, Melanie J., Durand, Laetitia, Langley, Emma, Coste-Sarguet, Lise, Zelent, Arthur, Chomienne, Christine, Kouzarides, Tony, Licht, Jonathan D., Guidez, Fabien

Journal:

Epigenetics & Chromatin

Année:

2015

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2015

The Promyelocytic Leukemia Zinc Finger Protein Affects Myeloid Cell Growth, Differentiation, and Apoptosis

Shaknovich, Rita, Yeyati, Patricia L., Ivins, Sarah, Melnick, Ari, Lempert, Cheryl, Waxman, Samuel, Zelent, Arthur, Licht, Jonathan D.

Journal:

Molecular and Cellular Biology

Année:

1998

Langue:

english

Fichier:

PDF, 528 KB

english, 1998

Benzodithiophenes Induce Differentiation and Apoptosis in Human Leukemia Cells

Jing, Yongkui, Hellinger, Nella, Xia, Lijuan, Monks, Anne, Sausville, Edward A., Zelent, Arthur, Waxman, Samuel

Journal:

Cancer Research

Année:

2005

Langue:

english

Fichier:

PDF, 611 KB

english, 2005

Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study

Swords, Ronan T., Azzam, Diana, Al-Ali, Hassan, Lohse, Ines, Volmar, Claude-Henry, Watts, Justin M., Perez, Aymee, Rodriguez, Ana, Vargas, Fernando, Elias, Roy, Vega, Francisco, Zelent, Arthur, Brothe

Journal:

Leukemia Research

Année:

2018

Langue:

english

Fichier:

PDF, 669 KB

english, 2018

A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy

Watts, Justin, Perez, Aymee, Pereira, Lutecia, Fan, Yao-Shan, Brown, Geoffrey, Vega, Francisco, Petrie, Kevin, Swords, Ronan, Zelent, Arthur

Journal:

International Journal of Molecular Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2017

Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase

Sbirkov, Yordan, Kwok, Colin, Bhamra, Amandeep, Thompson, Andrew, Gil, Veronica, Zelent, Arthur, Petrie, Kevin

Journal:

International Journal of Molecular Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 4.23 MB

english, 2017

RARÎ±1/RARÎ±2-PML mRNA Expression in Acute Promyelocytic Leukemia Cells: A Molecular and Laboratory-Clinical Correlative Study

Li, Yun-Ping, Andersen, Janet, Zelent, Arthur, Rao, Sreenivas, Paietta, Elisabeth, Tallman, Martin S., Wiernik, Peter H., Gallagher, Robert E.

Journal:

Blood

Année:

1997

Langue:

english

Fichier:

PDF, 261 KB

english, 1997

Reduced Retinoic Acid-Sensitivities of Nuclear Receptor Corepressor Binding to PML- and PLZF-RARÎ± Underlie Molecular Pathogenesis and Treatment of Acute Promyelocytic Leukemia

Guidez, Fabien, Ivins, Sarah, Zhu, Jun, SoÌderstroÌm, Mats, Waxman, Samuel, Zelent, Arthur

Journal:

Blood

Année:

1998

Langue:

english

Fichier:

PDF, 227 KB

english, 1998

A Novel BTB/POZ Transcriptional Repressor Protein Interacts With the Fanconi Anemia Group C Protein and PLZF

Hoatlin, Maureen E., Zhi, Yu, Ball, Helen, Silvey, Kirsten, Melnick, Ari, Stone, Stacie, Arai, Sally, Hawe, Nicola, Owen, Gareth, Zelent, Arthur, Licht, Jonathan D.

Journal:

Blood

Année:

1999

Fichier:

PDF, 411 KB

1999